Mechanism ya tripeptide yuburozi bwinzoka

Ubumara bwinzoka tripeptide

Isesengura risanzwe, HPLC≥98%

Izina ry'icyongereza: (2S) -beta-alanyl-l-prolyl-2, 4-Diamino-n - (phenylmethyl) acetate ya butanamide

Aliases: (2S) -beta-alanyl-l-prolyl 2, 4-diamino-n - (phenylmethyl) butyricoacetate;.SYN-AKE;inzoka-tripeptide;H - beta - Ala - Pro - Dab - NHBzl.2 acoh;Inzoka tr

Numero ya CAS: 823202-99-9

Inzira ya molekulari: C19H29N5O3.2 (C2H4O2)

Uburemere bwa molekile: 495.58

Iriburiro:

Urukurikirane: H-β-Ala-Pro-Dab-NH-Bzl

Kugaragara: Ifu yera

Intangiriro muri make:

Peptide yubumara bwinzoka mubyukuri ni peptide ntoya yigana ibikorwa byuburozi bwuburozi bwinzoka.Ntabwo ari ubumara bwinzoka, ahubwo nibikorwa byubaka polypeptide isa nuburozi bwinzoka.Peptide yubumara bwinzoka yakubye inshuro eshanu kugabanya imirongo ikora kurusha Botox, kandi mubizamini bya vivo byagaragaje ko nyuma yiminsi 28 yo gukoresha byagize ingaruka zigabanya iminkanyari 52%

Ingaruka:

1. Iminkanyari no kurwanya gusaza

2. Kuraho ingaruka zuruhu

3. Ibicuruzwa byawe bwite kumaso, ijosi n'amaboko

4. Kuruhura uruhu, gukora uruhu rwera, rworoshye kandi rworoshye, kunoza isura rusange

5. Irashobora kwinjira mu ruhu rwimbitse rwo mu maso, ikagumana uruhu, kandi igakuraho ibimenyetso byasigaye mu myaka

6. Kina ingaruka nziza kandi itanga amazi, kugirango uruhu rworohe kandi rworoshye, rwiza nkuko bisanzwe

7. Kuvomera, kurwanya-gusaza, kwerekana hydrata ya V ya oval isura, kugabanya urubyiruko rwo mumaso

8. Kurinda uruhu umusaruro wa melanin

Ingaruka:

Dipeptide diaminobutylbenzylamide diacetate / tripeptide yuburozi nka tripeptide irashobora gukoreshwa nkibicuruzwa kugirango bitezimbere neza kandi bitesha imbaraga imbaraga zo koroshya imitsi yo mumaso.Igikorwa tripeptide ikora kimwe na Waglerin1, urugingo rufunga neuromuscle mu burozi bwa TempleViper.Ubumara bwinzoka imeze nka tripeptide ikoreshwa kuri membrane ya postynaptic kandi irashobora kurwanya antagonistes ya nicotinic acetylcholine reseptor (nmAChR).Ubumara bwinzoka tripeptide ihuza nmAChRεsubunit kugirango wirinde guhuza acetylcholine no kuzuza reseptor, bivamo reseptor yuzuza ifunze, mubihe bifunze sodium ion ntishobora gukoreshwa, ntishobora depolarisation, guhagarika kwanduza imitsi, kuruhura imitsi.