Intangiriro ngufi kuri tidulutide

Uburyo bwibikorwa bya tidulutide Gattex (teduglutide)

Teduglutide ni analogue isanzwe yumuntu ya glucagon isa na peptide-2 (GLP-2), peptide isohorwa na selile L munda ya kure.GLP-2 izwiho kunoza amara no mu maraso kandi ikabuza gusohora aside gastric.Kuri dogere ya lu peptide na peptide reseptor 2 icyitegererezo cya glucagon, ibintu bikura nka insuline mu ngirabuzimafatizo zo mu mara, selile epithelia ya fibre fibre, subucosa na myenteric ihagaze hagati ya neurone yo munda.Gukora kwabo kwakirwa bitera gusohora kwamakuru mubitangazamakuru bitandukanye, harimo nka insuline imeze nkikura (IGF) 1, imikurire yimikorere ya selile nitorojeni ya azote na selile ikura (KGF).

Tidulutide, glucagon isa na peptide 2 (GLP-2) analogue, igabanya ubusa gastrica na metabolism kandi igenga imikurire, imyororokere no gukira kwingirangingo zo munda.Peptide yongereye umubare w'utugingo ngengabuzima, irashobora kongera kwinjiza amara mato, kugabanya impiswi.Indwara ngufi yo munda kubantu bakuru irashobora kuvurwa mubuvuzi.Ibiyobyabwenge bibaye imiti yambere isabwa kubantu badasanzwe ariko bafite intege nke cyane.

Intangiriro ngufi kuri tidulutide

Imiti ya molekuline ya tidulutide

Ibipimo fatizo

Izina: kuri c peptide (Teduglutide)

Umubare: GT - F027

Numero ya CAS: 197922-42-2

Urukurikirane: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys- Ile-Thr-Asp

Inzira ya molekulari: C164H252N44O55S

Uburemere bwa molekuline: 3752.08248